Molecular Nuclear Therapy is an innovative therapy which combines two approaches: tumor targeting and radiation therapy.
Unlike traditional chemotherapy drugs, which target both cancerous and healthy cells, Molecular Nuclear Therapies selectively target unhealthy cells: a “targeting molecule” brings a radioisotope in selected cells where its energy will be released and destroy targeted tissues.
This approach can lead to a more targeted and effective treatment with minimal side effects.
Lutetium Lu 177 dotatate (Lutathera) belongs to an innovative drug category called “Theragnostics” in which the same drug is used both in diagnostics and therapy. Lutetium Lu 177 dotatate (Lutathera) indeed emits two types of rays:
- a gamma ray, used to make SPECT (Single Photon Emission Computed Tomography) images, useful for treatment monitoring and follow up.
- and a beta particle, an energetic electron that destroys the DNA of the tumor cells.